Bruno P Imbimbo Selected Research

gantenerumab

2/2021	Can Anti-β-amyloid Monoclonal Antibodies Work in Autosomal Dominant Alzheimer Disease?
1/2018	The potential of solanezumab and gantenerumab to prevent Alzheimer's disease in people with inherited mutations that cause its early onset.
9/2014	Efficacy and safety studies of gantenerumab in patients with Alzheimer's disease.
3/2014	Is there still any hope for amyloid-based immunotherapy for Alzheimer's disease?

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Bruno P Imbimbo Research Topics

Disease

56	Alzheimer Disease (Alzheimer's Disease) 01/2023 - 11/2004
22	Cognitive Dysfunction 02/2021 - 05/2009
12	Dementia (Dementias) 02/2021 - 01/2010
9	Amyloid Plaque 10/2014 - 11/2004
6	Memory Disorders (Memory Loss) 07/2013 - 01/2010
4	Meningoencephalitis 03/2014 - 11/2010
4	Edema (Dropsy) 02/2012 - 11/2010
3	Neuroinflammatory Diseases 01/2021 - 09/2013
3	Disease Progression 01/2021 - 01/2009
2	Tauopathies 01/2022 - 01/2019
2	Inflammation (Inflammations) 01/2021 - 10/2019
2	Frontotemporal Dementia (Semantic Dementia) 01/2019 - 01/2016
2	Hypertension (High Blood Pressure) 01/2017 - 04/2013
2	Neuralgia (Stump Neuralgia) 08/2006 - 05/2005
1	Nervous System Diseases (Neurological Disorders) 01/2022
1	Hallucinations (Hallucination) 02/2021
1	Parkinsonian Disorders (Parkinsonism) 02/2021
1	Mitochondrial Diseases (Mitochondrial Disease) 09/2020
1	Dysbiosis 09/2020
1	Ewing Sarcoma (Sarcoma, Ewing) 01/2020
1	Sarcoma (Soft Tissue Sarcoma) 01/2020
1	Amyloidosis 11/2019
1	Neurobehavioral Manifestations 01/2018
1	Polyneuropathies (Polyneuropathy) 01/2018
1	Diabetes Mellitus 01/2017
1	Insulin Resistance 01/2017
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2017

Drug/Important Bio-Agent (IBA)

29	Amyloid (Amyloid Fibrils)IBA 01/2023 - 10/2010
16	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 04/2013 - 12/2007
14	Peptides (Polypeptides)IBA 10/2019 - 04/2007
9	Proteins (Proteins, Gene)FDA Link 02/2021 - 10/2010
9	Amyloid beta-PeptidesIBA 01/2010 - 04/2007
8	1- (3',4'- dichloro- 2- fluoro(1,1'- biphenyl)- 4- yl)cyclopropanecarboxylic acidIBA 09/2013 - 12/2007
7	tau Proteins (tau Protein)IBA 01/2022 - 12/2009
7	Monoclonal AntibodiesIBA 02/2021 - 11/2010
7	bapineuzumabIBA 10/2014 - 11/2010
6	solanezumabIBA 02/2021 - 02/2012
6	Pharmaceutical PreparationsIBA 01/2021 - 09/2005
5	AntibodiesIBA 01/2023 - 02/2012
5	ApolipoproteinsIBA 09/2020 - 08/2009
5	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2017 - 05/2009
5	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2017 - 05/2009
5	VaccinesIBA 03/2014 - 11/2010
5	EnzymesIBA 03/2011 - 01/2008
5	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2010 - 11/2004
4	Biomarkers (Surrogate Marker)IBA 02/2021 - 09/2013
4	gantenerumabIBA 02/2021 - 03/2014
4	Monounsaturated Fatty AcidsIBA 01/2017 - 01/2010
4	AN-1792IBA 03/2014 - 11/2010
3	Fatty Acids (Saturated Fatty Acids)IBA 01/2017 - 01/2010
3	Apolipoproteins E (ApoE)IBA 02/2012 - 01/2010
2	crenezumabIBA 02/2021 - 03/2014
2	Cholinergic Agents (Cholinergics)IBA 01/2021 - 12/2016
2	Glucose (Dextrose)FDA LinkGeneric 09/2020 - 01/2017
2	Interleukin-6 (Interleukin 6)IBA 01/2020 - 02/2010
2	Prealbumin (Transthyretin)IBA 11/2019 - 01/2018
2	N-Methylaspartate (NMDA)IBA 10/2019 - 05/2005
2	hydromethylthionineIBA 01/2016 - 01/2016
2	Humanized Monoclonal AntibodiesIBA 10/2014 - 09/2014
2	N2- ((2S)- 2- (3,5- difluorophenyl)- 2- hydroxyethanoyl)- N1- ((7S)- 5- methyl- 6- oxo- 6,7- dihydro- 5H- dibenzo(b,d)azepin- 7- yl)- L- alaninamideIBA 01/2010 - 07/2009
2	rofecoxib (Vioxx)FDA Link 01/2010 - 08/2009
2	Naproxen (Naprosyn)FDA LinkGeneric 01/2010 - 08/2009
2	Amyloid beta-Protein Precursor (Amyloid Protein Precursor)IBA 01/2010 - 01/2009
2	Neurotransmitter Agents (Neurotransmitter)IBA 12/2009 - 11/2009
2	Monoamine Oxidase (MAO)IBA 08/2006 - 05/2005
1	Investigational DrugsIBA 12/2021
1	Anticonvulsants (Antiepileptic Drugs)IBA 02/2021
1	APTIBA 02/2021
1	PresenilinsIBA 02/2021
1	Levodopa (L Dopa)FDA LinkGeneric 02/2021
1	Zonisamide (Zonegran)FDA LinkGeneric 02/2021
1	SulfonamidesIBA 02/2021
1	CytokinesIBA 01/2021
1	Complement C3 (C3 Complement)IBA 01/2021
1	LigandsIBA 01/2020
1	TATA-Box Binding Protein (TATA-Binding Protein)IBA 01/2020
1	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2020
1	RNA-Binding Protein FUSIBA 01/2020
1	Antiviral Agents (Antivirals)IBA 10/2019
1	Cholinesterase Inhibitors (Anticholinesterases)IBA 10/2019
1	Anti-Bacterial Agents (Antibiotics)IBA 10/2019
1	Carrier Proteins (Binding Protein)IBA 01/2019
1	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 01/2019
1	CholesterolIBA 01/2017
1	HDL CholesterolIBA 01/2017
1	Triglycerides (Triacylglycerol)IBA 01/2017
1	Amyloidogenic ProteinsIBA 12/2016
1	tau-protein kinaseIBA 01/2016
1	gosuranemabIBA 01/2016
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2016

Therapy/Procedure

14	Therapeutics 01/2022 - 01/2008
10	Immunotherapy 01/2019 - 04/2007
3	Secondary Prevention 01/2018 - 08/2009
2	Plasma Exchange 09/2020 - 01/2020
2	Institutionalization (Institutionalized Persons) 03/2013 - 01/2011
2	Mediterranean Diet 05/2011 - 01/2010
1	Immunomodulation 09/2020
1	Precision Medicine 01/2020
1	Glycemic Control 01/2017
1	Dietary Approaches To Stop Hypertension 01/2017